Cardiomagnyl instructions for use before or after meals. How to take cardiomagnyl before or after meals. At what pressure should Cordipin be taken: instructions for use

Cardiomagnyl is medicine, which is based on acetylsalicylic acid and magnesium hydroxide. Already from the name it becomes clear that this drug is used in cardiology to treat diseases of the cardiovascular system. It is available in tablets of 75 mg or 150 mg. Therefore, carefully look at the dosage of the drug in milligrams. So, how to take Cardiomagnyl to improve your health?

Methods of administration

The tablets are taken orally with a sufficient amount of water. Manufacturers do not prohibit chewing or crushing it before swallowing, so take it in a way that is convenient for you. Also, taking the drug is not affected by eating. In rare cases, if discomfort occurs in the gastrointestinal tract, Cardiomagnyl is prescribed after meals.

For primary prevention of cardiovascular diseases

For primary prevention, patients at risk are prescribed 150 mg on the first day, and 75 mg per day on subsequent days.

To prevent recurrent thrombosis and heart attack

Prescribe 150 mg of the drug per day. The dose can be divided into 2 doses.

Prevention of blood clots after surgery

After vascular surgery, 75-150 mg is prescribed once a day, depending on the complexity of the operation.

For chronic cardiac ischemia

For acute myocardial infarction and unstable angina

The dosage can reach 450 mg per day, depending on the severity of symptoms.

The duration of the course of treatment is always determined by the attending physician

Contraindications

the drug is not prescribed to patients under 18 years of age;
hypersensitivity to the components of the drug;
acute period of gastrointestinal ulcers;
severe impairment of kidney function;
pregnancy and lactation;
presence of bleeding in the gastrointestinal tract;
presence of a tendency to develop bleeding, hemophilia;
bronchial asthma;
simultaneous use with methotrexate;
The drug should be taken with caution in old age.

Cardiomagnyl also has mass side effects, affecting many organs and systems of the body, so it is strictly forbidden to take it without consulting a doctor.

Pathological processes in cardiovascular system kills a huge number of people every year. Diseases of this group lead in number deaths and the development of various dangerous complications against their background.

These diseases include myocardial infarction, strokes, thrombosis, thrombophlebitis and angina pectoris. And, most importantly, every pathology of this nature can be fought. One of the modern drugs is cardiomagnyl. Since its appearance on the market, it has established itself as effective remedy. Due to the increasing popularity of this drug, the question of how to properly take cardiomagnyl for prevention has begun to arise: in the morning or in the evening.

What does the drug represent?

Cardiomagnyl is a new generation product from the group of non-steroidal anti-inflammatory drugs. One of the active components of the pharmacological product is acetylsalicylic acid, that is, aspirin used by everyone.

For a long period of time, it was believed that such a substance was effective only as an antipyretic and anti-inflammatory. However, later scientists discovered another function - preventing thrombosis, that is, the formation of blood clots. This property has been clinically proven.

Cardiomagnyl

Unfortunately, not everything is so smooth: acetylsalicylic acid has its own significant drawback - a negative effect on organs gastrointestinal tract and the risk of hemorrhage. Long-term use of the substance leads to gastritis and stomach ulcers.

Please note that taking aspirin exclusively for a long period of time is harmful to the body and can lead to hemorrhage in the gastrointestinal tract!

That is why the second main component in Cardiomagnyl is magnesium hydroxide. Thanks to this substance, the negative effects of Aspirin are blocked.

This drug is also prescribed for varicose veins and post-traumatic arthrosis. However, before using Cardiomagnyl, it is important to obtain a recommendation from your doctor.

Mechanism of action

This remedy is practically a panacea, since it reduces the risk of developing dangerous diseases of the heart muscle and blood vessels. What happens in the body under the influence of Cardiomagnyl?

When acetylsalicylic acid enters the bloodstream, the synthesis of one of the enzymes - thromboxane, which is responsible for the adhesion of platelets - blood cells responsible for the clotting function - is blocked. Thanks to this effect, the development of blood clots is prevented.

This component also solves another problem: reducing the synthesis of prostaglandins involved in inflammatory process responsible for increasing body temperature.

The next component of Cardiomagnyl is magnesium hydroxide. The substance belongs to the group of antacids, that is, normalizing stomach acidity. Magnesium hydroxide blocks the negative effects of acid, thereby preventing the development of gastrointestinal pathology. It is worth noting that this component does not interact with acetylsalicylic acid and does not weaken its effect.

Blood thinning

Important! The drug has a cumulative effect; after the end of the course of use, it continues to have a beneficial effect for some time.

Indications

hypertension;
endocrine diseases ( diabetes mellitus);
sudden changes in pressure;
atherosclerosis;
angina pectoris;
overweight – obesity;
hereditary predisposition to the formation of blood clots.

Cardiomagnyl is used by both older people and those who abuse bad habits: smoking, drinking alcohol.

This drug is indicated:

People who have suffered thrombosis or myocardial infarction. Prevention of recurrence of attacks.
In the postoperative period for pathologies of the cardiovascular system.

Prevention of blood clots

In addition, many people wonder at what age to take this remedy. There is no clear answer to this question. Some doctors strongly discourage the use of Cardiomagnyl before the age of 18, but some suggest use from a much earlier age.

So that the drug gives maximum positive result and does not harm, contact a specialist who, depending on individual characteristics, will explain how to take it correctly and draw up a course.

Read also:, instructions, composition, analogues, prices and reviews

Contraindications and side effects

Almost any drug, along with its indications, also has contraindications. Cardiomagnyl is no exception. The instructions suggest a ban on taking the drug in the following cases:

in the first and last trimester of pregnancy, with gestosis and preeclampsia;
with renal failure;
for erosions and ulcers during exacerbation of pathology;
after hemorrhages in the brain;
with a lack of potassium, vitamin K;
when planning IVF;
in case of individual intolerance to the components of Cardiomagnyl;
with a tendency to hemorrhage;
for oncology;
during breastfeeding;
for bronchial asthma;
with bleeding in the gastrointestinal tract intestinal tract.

During pregnancy, the drug is not recommended for use, since salicylates penetrate into the blood and affect the development of the fetus. For the same reason, the pharmacological product is not used, or the dosage is significantly reduced, during breastfeeding.

On later Cardiomagnyl may cause bleeding in a pregnant woman. In this regard, taking the drug is dangerous to health and can lead to miscarriage.

Contraindication – pregnancy

The list of side effects is small, since Cardiomagnyl has a simple composition. Negative effects include general malaise, nausea, diarrhea, stomach pain, dizziness and tinnitus.

If you take the drug as prescribed by a cardiologist and follow all recommendations, then the risk of developing side effects extremely small.

Important! Under no circumstances should you start taking Cardiomagnyl on your own, as this can harm your body.

How long to take the drug?

In most cases, the drug is prescribed for a long period of time or even for life. In this case, exactly how long the course will last is determined only by the attending physician, based on individual characteristics and concomitant pathologies.

The drug has its own side effects, which also affect the duration of use. Most often, you have to take Cardiomagnyl for several years or your entire life. In this case, monitoring of blood clotting and blood pressure is mandatory.

That is why it is important to use the drug only on the recommendation and under the supervision of the treating cardiologist. Self-administration of Cardiomagnyl can cause the development of complications from internal organs.

When is the best time to take it?

Along with the question of whether it is possible to drink Cardiomagnyl for a long time for prevention, people are interested in when the effect of the drug is more pronounced.

In data official instructions and clinical studies do not indicate a specific time of day when Cardiomagnyl would be more effective, nor when to use the drug: after a meal or before.

Taking pills

Advice: It is safer to use Cardiomagnyl after meals and with milk.

In what quantities should I use the drug?

According to official data, for the primary prevention of stroke, thrombosis, myocardial infarction and other pathologies of blood vessels, heart, with secondary prevention and after surgical intervention on vessels, the recommended dose of the drug is one tablet per day.

It is worth noting that a correct and competent course can only be drawn up by the attending physician, depending on the individual characteristics, purpose of admission, and age.

Important! If the drug is taken by young people, and in cases where the risks of heart attack and other cardiovascular pathologies are low, internal bleeding may occur.

Interaction with other pharmacological products

Cardiomagnyl is a pharmacological product that reacts quite sharply with other groups of drugs. Therefore, before use, you should tell your doctor about all the medications you are taking in order to avoid various kinds of complications.

When taking thrombolytics and anticoagulants, the use of Cardiomagnyl is not recommended, since this drug enhances their effect several times and increases the risk of internal bleeding.

The drug is prohibited in combination with metatrexate. In addition, the main active ingredient of the drug, acetylsalicylic acid, increases the risk of developing gout in people who are at risk.

The simultaneous use of Ibuprofen and Cardiomagnyl reduces the effectiveness of the latter several times. Negative effects are observed when antacids are taken simultaneously, since the rate and intensity of absorption of acetylsalicylic acid into the bloodstream decreases several times.

Interaction with others

If the level of uric acid in the blood is high, taking the drug can only make things worse for the patient. If a person arterial hypertension uncontrollable, then taking this drug will not only not reduce the risk of developing cardiovascular diseases, but will also increase the risk of hemorrhagic stroke.

Important! Before surgery, you need to stop taking Cardiomagnyl, since acetylsalicylic acid thins the blood.

One of the modern drugs, Cardiomagnyl, has a positive effect in the prevention of cardiovascular diseases: myocardial infarction, stroke, thrombophlebitis, thrombosis. In addition, the drug is used in the therapeutic course of varicose veins and arthrosis.

Cardiomagnyl contains 75 mg acetylsalicylic acid and 15.2 mg, the drug Cardiomagnyl Forte contains active substances in a ratio of 150/30.39 mg, respectively.

Auxiliary components: magnesium hydroxide and stearate, corn and potato starch, MCC, talc, methyloxypropylcellulose 15, macrogol.

Release form

Cardiomagnyl tablets 75 mg po.
Tablets Cardiomagnyl Forte 150 mg po.

Tablets 75/15.2 mg are available in the shape of a stylized “heart”, their color is white. Forte tablets are oval-shaped, white, with a score line on one side.

pharmachologic effect

Reduces the ability of blood cells (in particular, ) to aggregation and reduces the risk of formation blood clots .

Pharmacodynamics and pharmacokinetics

Wikipedia states that acetylsalicylic acid is a salicylic ester of acetic (ethanoic) acid and has the ability to relieve pain, relieve heat and inflammation, and also prevent aggregation platelets .

Acetylsalicylic acid (ASA) irreversibly inhibits the COX-1 enzyme, resulting in the blocking of an important mediator of aggregation and degranulation platelets TXA-2 and aggregation is suppressed platelets .

ASA is absorbed from the gastrointestinal tract almost completely. T1/2 of the substance - about 15 minutes. This rate of elimination is due to the fact that in the blood plasma, liver and intestines acetylsalicylic acid quickly hydrolyzes to salicylic acid (SA).

The category of frequent (reported with a frequency of 0.01 to 0.1) side effects includes: insomnia, headache, bronchospasm (in patients with bronchial asthma ), erosive lesions of the upper digestive canal, diarrhea, nausea, vomiting, dyspepsia, skin rashes of various types, purpura , , angioedema , erythema multiforme , acute epidermal necrolysis , Stevens-Johnson syndrome .

Some patients may:

hidden bleeding;
anaphylactic reactions;
tinnitus;
ulceration of the walls of the digestive canal in its upper section (in extremely rare cases, the lower section may also be affected);
melena;
vomiting blood;
perforation of the walls of the digestive canal and the development of gastrointestinal bleeding;
hypoglycemia;
drowsiness;
vertigo;
intracerebral bleeding;
anemia (in patients who receive Cardiomagnyl for a long period of time);
changes in the blood picture (decrease in the concentration of prothrombin, platelets, neutrophils, leukocytes in the blood; eosinophilia, aplastic anemia; increased levels of alkaline phosphatase and transaminases);
esophagitis;
formation of strictures in the digestive canal;
exacerbation of spastic colitis.

Dose-dependent side effects: acute hepatitis moderate severity, hearing loss and deafness. The phenomena are reversible.

Cardiomagnyl tablets: instructions for use

Instructions for use of Cardiomagnyl

For ischemic heart disease (in any form), the starting dose is 150 mg/day. For maintenance treatment, half the dose is prescribed.

When unstable angina pectoris /acute myocardial infarction, the optimal dosage is from 150 to 450 mg/day. Treatment should be started as soon as possible after the onset of symptoms.

How to take Cardiomagnyl for prevention?

To prevent re-formation blood clots on initial stages treatment, the patient is prescribed 150, then 75 mg/day.

Prophylactic dose to prevent CV events (e.g. acute coronary syndrome ) and thrombosis - 75 mg/day.

Why is Cardiomagnyl Forte prescribed, and what is the optimal dosage?

Forte tablets are indicated for patients with coronary artery disease. Treatment begins by prescribing 1 tablet per day to the patient. and subsequently switch to half the maintenance dose.

How to take the pills?

The medicine is swallowed whole (if impossible, the tablet can be chewed, ground into powder or broken in half) with liquid.

How to take it correctly - morning or evening?

The manufacturer's instructions do not provide clear instructions as to what time of day to take Cardiomagnyl tablets.

Doctors, answering the question “When is it better to take the drug - in the morning or in the evening?”, recommend taking the medicine in the evening, about 60 minutes after dinner.

How long can I take the drug?

The duration of treatment depends on the course and severity of the disease.

In some cases (according to indications, taking into account contraindications and subject to periodic monitoring of blood pressure and hemocoagulation), the drug can be prescribed for life.

How long to take the drug can only be determined by the attending physician.

Overdose

For an adult, a dose of 150 mg/kg is considered dangerous.

A long course of treatment using high doses can cause chronic intoxication, which manifests itself:

the appearance of ringing in the ears;
vasodilation;
nausea;
dizziness;
deafness;
vomiting;
headache;
disturbance of consciousness;
sweating

Symptoms of acute poisoning due to overdose are:
heat;

hyperventilation;
anxiety;
acid-base imbalance ( gas (respiratory )alkalosis , metabolic acidosis ).

In case of severe poisoning, CNS depression syndrome develops, which, in turn, can lead to cardiovascular collapse , , respiratory arrest.

Acute ASA poisoning - when taking a dose exceeding 300 mg/kg - often causes acute liver failure. A dose exceeding 500 mg/kg is lethal.

Treatment for acute overdose: gastric lavage, administration of enterosorbents, restoration of electrolyte and fluid balance to avoid dehydration, , hyperkalemia And hyperpyrexia .

For derivation salicylic acid from blood plasma they resort to forced alkaline diuresis , hemoperfusion or .

Interaction

Cardiomagnyl potentiates the effects:

anticoagulants ;
hypoglycemic drugs ;
methotrexate ;

Reduces the effectiveness of ACE inhibitors, And .

TOolestyramine And antacids impair drug absorption.

Since Mg is included in the drug in small quantities, the clinical significance of its interaction with the ASA contained in the tablets is minimal.

The drug is not intended for the treatment of children and adolescents.

It does not slow down the speed of reactions, so there are no restrictions regarding driving vehicles/machinery during its use.

What can replace Cardiomagnyl?

Analogues of Cardiomagnyl by ATC code, composition of active ingredients and release form: Akard , Asacyl-A , Aspeter , , Acetylsalicylic acid , , , Thrombolic Cardio , Thrombogard , Ekorin .

Analogues of the drug with a similar mechanism of action: Avix , Agrenox , Aspigrel , , Vasotic , Monofram , Deplatte , , Ipaton , , Clopyletes , Lopigrol , Miogrel , Plavigrel , , Trombex , Effient .

The price of Cardiomagnyl analogues is from 8 rubles.

Which is better: Cardiomagnyl or Thromboass?

Thrombo ACC tablets are an NSAID used for the prevention stroke , heart attack , , thromboembolism and a number of other pathological conditions. The basis of the drug - acetylsalicylic acid .

The principle of action of Cardiomagnyl and its analogue is based on the ability of ASA to block the synthesis of thromboxane and Pg, which helps reduce aggregation and adhesion platelets , as well as reducing inflammation.

In addition, both drugs reduce the content of K-dependent coagulation factors and increase plasma activity.

The main differences between Cardiomagnyl and its substitute are: composition and release form. Trombo ACC tablets contain 50 or 100 mg of ASA, and do not contain magnesium hydroxide. To minimize the negative effects of ASA, tablets are coated with a special enteric protective coating.

Patients leave approximately the same reviews about the drugs, but Thrombo ACC, in their subjective opinion, is somewhat less likely to cause unwanted side reactions.

Acecardol and Cardiomagnyl - differences

is a drug whose active ingredient is also ASA. Its differences from Cardiomagnyl are the absence of magnesium hydroxide in the composition, the release form (tablets in a red coating) and the dosage of ASA (50/100/300 mg/tablet).

Which is better: Cardiomagnyl or Aspirin Cardio?

Aspirin Cardio is an original drug from Bayer AG. The drug belongs to the group of ASA drugs with the largest evidence base. Thanks to a special enteric coating, its active substance is released not in the stomach, but in the intestinal tract, so Aspirin Cardio is better tolerated by patients than regular Aspirin acetylsalicylic acid .

The tablets are produced in calendar packaging, which makes it possible to improve control over the patient’s compliance with the treatment prescribed by the doctor.

Alcohol compatibility

With simultaneous intake of alcohol and ASA, an additive effect is observed.

Cardiomagnyl during pregnancy

In the 1st trimester, taking high doses of salicylates is associated with an increased incidence of fetal developmental defects.

In the 2nd trimester, drugs of this group are used taking into account the therapeutic effect for the mother’s body and the potential risks for the unborn child.

In the last 3 months of pregnancy, salicylates are contraindicated. In the 3rd trimester, high doses of ASA can cause inhibition of labor, increased bleeding (both in the mother and the fetus), and premature closure of the ductus botallus in the fetus.

The use of ASA immediately before childbirth can provoke hemorrhagic cerebrovascular accident (especially in premature infants).

Salicylates and their metabolic products pass into breast milk. Accidental intake of a small dose of ASA during lactation does not require cessation of breastfeeding and is not accompanied by the development of undesirable effects in the child. However, high doses or long-term use of these drugs requires discontinuation of breastfeeding.

Reviews during pregnancy allow us to conclude that most often the drug is prescribed to prevent thrombotic complications in risk groups, in complex therapy placental insufficiency and gestosis , as well as for treatment polyhydramnios .

Almost all expectant mothers noted that Cardiomagnyl was well tolerated, and improvements (in particular, a decrease in viscosity and an increase in blood mobility) became noticeable after 10-14 days of treatment.

Reviews of Cardiomagnyl

There are different reviews about Cardiomagnyl on the forums. Most patients who take these tablets as prescribed by their doctor are satisfied with them, but sometimes there are negative reviews. The main reasons for the low rating of the product are its high price and side effects.

Research results and expert reviews allow us to conclude that ASA is the main drug antithrombotic therapy in patients at risk cardiovascular pathologies (including those arising during pregnancy).

An important feature of the drug Cardiomagnyl is the presence in its composition of Mg hydroxide - a “buffer” that prevents the occurrence of the damaging effects of ASA and, in particular, erythematous-hemorrhagic form of NSAID gastropathy .

Studies have shown that Cardiomagnyl is more effective than enteric dosage forms in inhibiting aggregation platelets . In this case, the frequency adverse reactions from the digestive system was the lowest compared to normal And aspirin , which is available in the form of enteric tablets.

Thus, having the same indications and contraindications for use as conventional ASA, Cardiomagnyl is a much safer, but no less effective means for preventing complications of CVD diseases.

Cardiomagnyl price: how much does 75 mg/15.2 mg and 150 mg/30.39 mg cost?

The average price of Cardiomagnyl tablets 75 mg No. 100 in Ukrainian pharmacies is 85 UAH. You can buy Forte tablets for 95-98 UAH (package No. 100). At the same time, the cost of the drug in Zaporozhye, Kyiv, Kharkov or Odessa differs slightly.

The price of Cardiomagnyl in Moscow and St. Petersburg is from 120 rubles. for package No. 30 and from 215 rubles. per package No. 100. The cost of Forte tablets is from 125 per package No. 30 and 260 rubles. and from per package No. 100.

Online pharmacies in Russia Russia
Online pharmacies in Ukraine Ukraine
Online pharmacies in Kazakhstan Kazakhstan

ZdravCity

Cardiomagnyl tab. p.p.o. 75mg+15.2mg n100Takeda Pharmaceuticals LLC

Cardiomagnyl tab. p.p.o. 150mg+30.39mg n30Nycomed Gmbh/Takeda Gmbh/Takeda Pharmaceuticals LLC

Cardiomagnyl tab. p.p.o. 75mg+15.2mg n30Nycomed GmbH/Takeda GmbH

Many people ask these questions:

How to take Cardiomagnyl correctly?
What time of day is best to take?
How many times a day should I take it?
How long can you take Cardiomagnyl without interruption?
At what age can it be taken?

Let's look at these questions.

The official instructions for the drug do not indicate a specific time for taking the medicine, and there are also no instructions about taking it before or after meals.

Therefore, you can take Cardiomagnyl at any time convenient for you.

If necessary, the tablet can be pre-crushed or chewed.

But since the active substance of Cardiomagnyl is acetylsalicylic acid, which has an irritating effect on the walls of the stomach, it is still better to take it as a whole tablet.

Try to take the medicine at the same time every day.

According to the official instructions for the initial prevention of cardiovascular diseases, for the prevention of recurrent myocardial infarction and blood vessel thrombosis, for the prevention after surgical operations on blood vessels and unstable angina - 1 Cardiomagnyl tablet containing aspirin at a dose of 75 mg (heart-shaped tablets) or 150 mg (oval-shaped) 1 time per day.

The exact dosage of the medicine is prescribed by the doctor, depending on the patient’s condition.

If there are no contraindications and no side effects, then Cardiomagnyl is taken in courses or for life - it all depends on the prescription of your attending physician.

After 6 months, you can take a short two-week break and then resume taking it again.

Cardiomagnyl can be taken after reaching 18 years of age; before this age, the drug is contraindicated.

We think the article helped you and you received an answer to the question: How to take Cardiomagnyl correctly?

And now you know how to take Cardiomagnyl correctly? What time of day is best to take it? How many times a day should I take and for how long can I take the drug without a break and from what age?

Victoria Burova

I buy it for my 75-year-old grandmother as a preventive measure for stroke and heart attack (doctor’s recommendation). Grandmother drinks after meals and in a small dosage - 75 mg. Feels much better.

Sergey Kirov

I take Cardiomagnyl 1 tablet at night - the cramps have become less.

Igor Bogdanov

And the doctor prescribed me to use it for life. Now I take it before bed and wash it down with milk.

Tatiana Baletskaya

I have been taking Cardiomagnyl for 2.5 years, although the doctor first prescribed aspirin. But I read that magnesium eliminates the aggressive effect of aspirin on the gastric mucosa and started taking Cardiomagnyl. I always drink it in the morning or during or after meals. My hemoglobin is higher than normal (about 147-157), the hospital said that I have Iron-deficiency anemia, since such a high figure. About 6 years ago I was treating an ulcer, while taking the medicine it did not get worse, but erosive gastritis escalated twice. In such cases, medications with aspirin are prohibited, but unfortunately we do not prescribe anything else.

Sergey Ostrovsky

I am 79 years old. I have already suffered four heart attacks, I have been taking Cardiomagnyl for about 15 years, without a break. I haven’t had any problems with my stomach, but for arrhythmias I also drink a decoction of willow bark.

Svetlana Amelina

It’s better to take it after meals; I don’t see any point in drinking it in the morning. It is better to take it in the evening after dinner, because the risk of blood clots is many times greater in the evening and at night.

Anastasia Sheiman

I've been drinking for over a year now. I have acquired an increase in uric acid, which is what is written in the instructions “in small doses, aspirin can provoke the development of gout...”. She refused the drug herself. I will be treated folk remedies. They say garlic, sweet clover, and lemon help thin the blood very well.

Denis Borisov

For a very long time I drank acetyl for 5 rubles, it’s great for the heart. But before the FGS operation, I received gastritis of the stomach. Now, according to the doctor’s recommendations, I’m switching to Cardiomagnyl. I trust my doctor.

Natalya Khmelevskaya

And I heard from friends that you should drink Cardiomagnyl in the evening with oatmeal jelly.

Maxim Nesterenko

I drink Cardiomagnyl all the time. I forgot about the arrhythmia, the dizziness went away. I take it in the morning.

Anya Polonskaya

A friend of mine was prescribed Cardiomagnyl after a stroke. He says he feels just fine.

Polina Alekseeva

The doctor prescribed it to me after a heart attack and told me to take it for life.

And a little video with advice from a cardiologist

How long can you take Cardiomagnyl? This question interests many people. Therefore, in this article we will give a comprehensive answer to it. You will also learn about the purpose for which this medication is prescribed by doctors, what features it has, etc.

Before answering the question of how long you can take Cardiomagnyl, it should be said that these are heart-shaped tablets, the main active ingredient of which is acetylsalicylic acid.

Today, this drug has gained wide popularity among people suffering from diseases of the cardiovascular system, which often lead to heart attack and stroke. This remedy is designed to thin the patient’s blood and prevent platelets from sticking together.

Most often, the question of how long you can take Cardiomagnyl is asked by people over 40 years of age. And this is not without reason. After all, it is during this period that the human body experiences hormonal changes, and substances appear in the blood that help accelerate platelet aggregation. This process not only increases the thickness of the blood, but also causes the formation of blood clots, which significantly increases the risk of heart attack and stroke.

To thin the plasma, aspirin-type drugs are often prescribed to hypertensive patients and patients with atherosclerosis. These include the drug “Cardiomagnyl”. For patients who have suffered a stroke, this drug is prescribed to prevent the mentioned pathological phenomenon. However, only an experienced doctor can decide how long and how much to take Cardiomagnyl.

How to take Cardiomagnyl correctly? Is this drug necessary for people with a healthy cardiovascular system? Only an experienced doctor can answer all these questions.

Before prescribing this medication, the doctor must refer the patient for a blood test to detect blood clotting. If the results are poor, the specialist recommends taking aspirin-type drugs for 10 days, after which he advises repeating the test procedure.

This technique allows you to determine how well the medication acts and thins the blood. Only after this “Cardiomagnyl” is prescribed as a course, of course, provided that the patient has no contraindications.

How long can you take Cardiomagnyl without interruption? This question was asked by almost everyone who was prescribed this medicine. However, only a specialist can answer it.

According to most doctors, people suffering from cardiovascular pathologies are prescribed this drug for life. This requires constant and careful monitoring of blood clotting.

So why do many people ask how long can they take Cardiomagnyl? This curiosity is not due to excessive concern for one’s blood vessels and heart, but to the fact that with prolonged use of drugs containing aspirin, severe gastric bleeding can occur quite quickly, and an ulcer can also develop. duodenum or stomach. That is why it is important not only to know how long you can take Cardiomagnyl, but also to follow all the doctor’s recommendations, including the dosage of this drug. As a rule, it is 75-150 mg once a day. In this case, the heart-shaped tablets should be swallowed whole and washed down with plain water or milk. If desired, it can be broken in half, or pre-grinded or chewed.

When is the best time to take Cardiomagnyl? Considering that the frequency of taking the medication in question is once a day, it can be taken at any time. However, experts do not recommend doing this on an empty stomach. Thus, taking aspirin should be taken with breakfast, lunch or dinner. However, the attached instructions say that the manufacturer of this drug does not have clear instructions about exactly when to take Cardiomagnyl tablets. As for doctors, almost all of them claim that this medication is best taken in the evening, about an hour after dinner.

For better absorption of the drug, it is better to grind the tablets into powder before using it.

The duration of use of the drug in question in preventive and medicinal purposes depends on the severity and characteristics of the disease.

Sometimes, for strict indications, as well as taking into account prohibitions on use and subject to constant monitoring of hemocoagulation and blood pressure, this drug can be prescribed for life.

It should also be noted that very often doctors advise their patients to take Cardiomagnyl tablets in courses. The medicine should be taken continuously for 10 days, and then take a break for a similar amount of time.

Sometimes the question of how long you can take a medicine like Cardiomagnyl is asked by pregnant women. According to the instructions, during this period the use of this medication is undesirable, especially in the first two trimesters. If such a need still exists, the attending physician is obliged to assess the benefit-risk ratio and prescribe the medication in a minimum dose. By the way, in the third trimester of pregnancy, taking this drug is strictly prohibited.

It is imperative to follow the recommended dosages of Cardiomagnyl. This is due to the fact that the use of large quantities of the drug can pose a real threat to the patient's health. For an adult dangerous dose 150 mg/kg of the drug in question is considered.

It should also be said that a long course of treatment with high doses of the drug can cause chronic intoxication, which manifests itself in the following:

nausea;
tinnitus;
deafness;
vasodilation;
vomit;
dizziness;
headache;
disturbance of consciousness;
sweating

As for the symptoms of acute poisoning, they are expressed as follows:

hyperventilation;
anxiety;
disturbance of acid-base balance.

It should also be noted that in case of severe poisoning, the patient may develop CNS depression syndrome, which will ultimately lead to coma, cardiovascular collapse and respiratory arrest.

When all the described symptoms are observed, the stomach is washed and the balance of fluids and electrolytes is restored, enterosorbents are prescribed and forced diuresis is used.

Now you know how long you can take Cardiomagnyl. If purchasing such a medication is not available to you, then it can be replaced with analogues. These include drugs such as Trombass, Curantil (for pregnant women), Acecardol, Aspirin Cardio and others. It should be noted that before using all of the above remedies, it is also necessary to consult with a specialist.

The drug is classified as a medicine that prevents blood clots. When should you take Cardiomagnyl, morning or evening? Its main effect is to reduce the formation of blood clots in the lumen of blood vessels and prevent the occurrence of acute heart attacks myocardium, as well as the drug is used for disorders of cerebral microcirculation with damage to brain tissue. The drug should be used according to the instructions for use.

"Cardiomagnyl": composition

The main active ingredient is acetylsalicylic acid; in addition to it, the drug also contains the following auxiliary components:

magnesium hydroxide;
potato starch;
cellulose;
a compound of magnesium salt and stearic acid.

"Cardiomagnyl" is sold in pharmacies in the form of tablets, which are packaged in bottles (30 or 100 pieces).

In pharmacies you can purchase a drug from the manufacturer “Nycomed” with different ratios of active ingredients:

In the first case, the tablets are produced in the shape of hearts. The ratio of acetylsalicylic acid and magnesium hydroxide is seventy-five and fifteen milligrams. The cost of thirty tablets is 150 rubles, the price of one hundred tablets is 260 rubles.
The second type is available in the form of oval tablets. The content of active substances is one hundred fifty and thirty milligrams. The cost of "Cardiomagnyl" is 350 rubles.

For what diseases is the drug used?

The drug is effective in the fight against the following ailments:

To prevent recurrence of thrombosis, as well as after surgery, which helps to restore blood circulation in the arteries of the heart (using shunts).
With organic and functional lesions of the myocardium, which are caused by a lack of blood supply to the heart muscle.
With a focus of infarction developing as a result of acute damage to the coronary microcirculation.
With thrombosis (intravital formation of clots inside blood vessels that impede the free flow of blood through the circulatory system).
For headaches.
For serious and life-threatening pathological disorders of cerebral circulation.

The drug is also used to prevent heart and vascular diseases in patients over fifty-five years of age if they have diabetes, excessive weight gain and high blood pressure. When to take Cardiomagnyl - is it best in the morning or evening?

pharmachologic effect

The medicine belongs to the group of non-steroidal drugs that have anti-inflammatory and anti-thrombosis effects:

Acetylsalicylic acid reduces the rate of chemical reactions in the enzyme that is involved in the formation of prostanoids. In addition, the element inhibits the process of combining thromboxane A2, as a result of which the process of connecting blood clots stops and blood clotting decreases.
Magnesium hydroxide is considered the second important element that is part of the drug. It helps protect the mucous membrane of the stomach and intestines, thereby reducing the risk of developing negative reactions (stomach ulcers, gastrointestinal hemorrhages).

The medication is administered orally. Capsules must be taken whole with water. The drug can be taken regardless of nutrition, but, as a rule, to prevent adverse reactions, it is better to take the drug after meals:

For unstable angina, take one tablet containing acetylsalicylic acid in a dosage of 75 to 150 milligrams in the morning or evening.
When to take Cardiomagnyl to prevent recurrence of myocardial infarction, as well as thrombosis? If you have these diseases, the drug can be taken at any time of the day. Prescribe one tablet in a dose of up to 150 milligrams once a day.

To exclude the occurrence of acute blockage of blood vessels (thromboembolism) after surgery, take 1 tablet in the same dosage as for myocardial infarction.

For what disorders is the drug prescribed?

For primary prevention of heart diseases, Cardiomagnyl is prescribed in the presence of the following deviations:

diabetes;
hyperlipidemia;
persistent increase in pressure;
obesity;
smoking.

When to take Cardiomagnyl - morning or evening? In such cases, one tablet of the drug is prescribed on the first day at a dosage of 150 milligrams, on the second day and subsequent days, one tablet at a dose of 75 milligrams at any time of the day. The duration of therapy depends on many factors, as well as the severity of the disease. In rare cases, Cardiomagnyl may be prescribed for life. The drug can be purchased at any pharmacy without a prescription.

According to reviews, Cardiomagnyl perfectly helps to cope with diseases of the heart and blood vessels, and also helps thin the blood. If you take the drug according to the doctor’s instructions and inform him about all aspects of your health, you can avoid the occurrence of side effects. Patients can take Cardiomagnyl in the morning and evening, whenever it is convenient for them.

Pathological processes in the cardiovascular system annually claim the lives of a huge number of people. Diseases of this group lead in the number of deaths and the development of various dangerous complications against them.

These diseases include myocardial infarction, strokes, thrombosis, thrombophlebitis and angina pectoris. And, most importantly, every pathology of this nature can be fought. One of the modern drugs is cardiomagnyl. Since its appearance on the market, it has established itself as an effective remedy. Due to the increasing popularity of this drug, the question of how to properly take cardiomagnyl for prevention has begun to arise: in the morning or in the evening.

Cardiomagnyl

Unfortunately, not everything is so smooth: acetylsalicylic acid has its own significant drawback - a negative effect on the gastrointestinal tract and the risk of hemorrhages. Long-term use of the substance leads to gastritis and stomach ulcers.

Please note that taking aspirin exclusively for a long period of time is harmful to the body and can lead to hemorrhage in the gastrointestinal tract!

That is why the second main component in Cardiomagnyl is magnesium hydroxide. Thanks to this substance, the negative effects of Aspirin are blocked.

This drug is also prescribed for varicose veins and post-traumatic arthrosis. However, before using Cardiomagnyl, it is important to obtain a recommendation from your doctor.

This remedy is practically a panacea, since it reduces the risk of developing dangerous diseases of the heart muscle and blood vessels. What happens in the body under the influence of Cardiomagnyl?

This component also solves another problem: reducing the synthesis of prostaglandins involved in the inflammatory process and responsible for increasing body temperature.

Blood thinning

Important! The drug has a cumulative effect; after the end of the course of use, it continues to have a beneficial effect for some time.

hypertension;
endocrine diseases (diabetes mellitus);
sudden changes in pressure;
atherosclerosis;
angina pectoris;
overweight – obesity;
hereditary predisposition to the formation of blood clots.

Cardiomagnyl is used by both older people and those who abuse bad habits: smoking, drinking alcohol.

This drug is indicated:

People who have suffered thrombosis or myocardial infarction. Prevention of recurrence of attacks.
In the postoperative period for pathologies of the cardiovascular system.

Prevention of blood clots

In order for the drug to give the most positive result and not cause harm, contact a specialist who, depending on your individual characteristics, will explain how to take it correctly and draw up a course.

Almost any drug, along with its indications, also has contraindications. Cardiomagnyl is no exception. The instructions suggest a ban on taking the drug in the following cases:

in the first and last trimester of pregnancy, with gestosis and preeclampsia;
with renal failure;
for erosions and ulcers during exacerbation of pathology;
after hemorrhages in the brain;
with a lack of potassium, vitamin K;
when planning IVF;
in case of individual intolerance to the components of Cardiomagnyl;
with a tendency to hemorrhage;
for oncology;
during breastfeeding;
for bronchial asthma;
with bleeding in the gastrointestinal tract.

In later stages, Cardiomagnyl can cause bleeding in a pregnant woman. In this regard, taking the drug is dangerous to health and can lead to miscarriage.

Contraindication – pregnancy

The list of side effects is small, since Cardiomagnyl has a simple composition. Negative effects include general malaise, nausea, diarrhea, stomach pain, dizziness and tinnitus.

If you take the drug as prescribed by a cardiologist and follow all recommendations, then the risk of side effects is extremely low.

Important! Under no circumstances should you start taking Cardiomagnyl on your own, as this can harm your body.

Along with the question of whether it is possible to drink Cardiomagnyl for a long time for prevention, people are interested in when the effect of the drug is more pronounced.

The official instructions and clinical studies do not indicate a specific time of day when Cardiomagnyl would be more effective, nor when to use the drug: after a meal or before.

Advice: It is safer to use Cardiomagnyl after meals and with milk.

According to official data, for the primary prevention of stroke, thrombosis, myocardial infarction and other vascular and heart pathologies, for secondary prevention and after vascular surgery, the recommended dose of the drug is one tablet per day.

It is worth noting that a correct and competent course can only be drawn up by the attending physician, depending on the individual characteristics, purpose of admission, and age.

Important! If the drug is taken by young people, and in cases where the risks of heart attack and other cardiovascular pathologies are low, internal bleeding may occur.

When taking thrombolytics and anticoagulants, the use of Cardiomagnyl is not recommended, since this drug enhances their effect several times and increases the risk of internal bleeding.

The drug is prohibited in combination with metatrexate. In addition, the main active ingredient of the drug, acetylsalicylic acid, increases the risk of developing gout in people who are at risk.

Interaction with others

If the level of uric acid in the blood is high, taking the drug can only make things worse for the patient. If a person has uncontrolled arterial hypertension, then taking this drug will not only not reduce the risk of developing cardiovascular diseases, but will also increase the risk of hemorrhagic stroke.

Important! Before surgery, you need to stop taking Cardiomagnyl, since acetylsalicylic acid thins the blood.

The active ingredients of Cardiomagnyl are acetylsalicylic acid and magnesium hydroxide. If the drug is used incorrectly, the first component can cause internal hemorrhage. The drug has a fairly wide list of contraindications; before use, consultation with a doctor is required.

In this article you can find instructions for use medicinal product Cardiomagnyl. Feedback from site visitors - consumers - is presented of this medicine, as well as the opinions of specialist doctors on the use of Cardiomagnyl in their practice. We kindly ask you to actively add your reviews about the drug: whether the medicine helped or did not help get rid of the disease, what complications and side effects were observed, perhaps not stated by the manufacturer in the annotation. Analogues of Cardiomagnyl in the presence of existing structural analogues. Use for the treatment of prevention of cardiovascular diseases, myocardial infarction and thrombosis in adults, including during pregnancy and lactation.

Cardiomagnyl- non-steroidal anti-inflammatory drug, antiplatelet agent. The mechanism of action of acetylsalicylic acid (the active ingredient of the drug Cardiomagnyl) is based on the irreversible inhibition of the COX-1 enzyme, as a result of which the synthesis of thromboxane A2 is blocked and platelet aggregation is suppressed. It is believed that acetylsalicylic acid has other mechanisms for suppressing platelet aggregation, which expands the scope of its use in various vascular diseases. Acetylsalicylic acid also has anti-inflammatory, analgesic and antipyretic effects.

Magnesium hydroxide, which is part of Cardiomagnyl, protects the gastrointestinal mucosa from the effects of acetylsalicylic acid.

Pharmacokinetics

After taking the drug orally, acetylsalicylic acid (aspirin) is absorbed from the gastrointestinal tract almost completely.

Magnesium hydroxide (in the doses used) does not affect the bioavailability of acetylsalicylic acid.

Indications

primary prevention of cardiovascular diseases such as thrombosis and acute heart failure in the presence of risk factors (for example, diabetes mellitus, hyperlipidemia, hypertension, obesity, smoking, elderly age);
prevention of recurrent myocardial infarction and blood vessel thrombosis;
prevention of thromboembolism after vascular surgery (coronary artery bypass grafting, percutaneous transluminal coronary angioplasty);
unstable angina.

Release forms

Tablets, coated film-coated 75 mg and 150 mg.

Instructions for use and dosage

The tablets should be swallowed whole with water. If desired, the tablet can be broken in half, chewed or pre-grown.

For the primary prevention of cardiovascular diseases such as thrombosis and acute heart failure in the presence of risk factors (for example, diabetes mellitus, hyperlipidemia, arterial hypertension, obesity, smoking, old age), 1 tablet of Cardiomagnyl containing acetylsalicylic acid (aspirin) is prescribed. dose of 150 mg on the first day, then 1 tablet of Cardiomagnyl containing acetylsalicylic acid in a dose of 75 mg 1 time per day.

To prevent recurrent myocardial infarction and thrombosis of blood vessels, 1 tablet of Cardiomagnyl containing acetylsalicylic acid in a dose of 75-150 mg is prescribed once a day.

To prevent thromboembolism after vascular surgery (coronary artery bypass grafting, percutaneous transluminal coronary angioplasty), 1 tablet of Cardiomagnyl containing acetylsalicylic acid in a dose of 75-150 mg is prescribed once a day.

For unstable angina, 1 tablet of Cardiomagnyl containing acetylsalicylic acid in a dose of 75-150 mg is prescribed once a day.

Side effect

hives;
Quincke's edema;
anaphylactic reactions;
heartburn;
nausea, vomiting;
pain in the abdominal area;
ulcers of the mucous membrane of the stomach and duodenum;
gastrointestinal bleeding;
perforation of a gastric or duodenal ulcer;
stomatitis;
esophagitis;
strictures;
colitis;
bronchospasm;
increased bleeding;
anemia;
hypoprothrombinemia, thrombocytopenia, neutropenia, eosinophilia, agranulocytosis;
dizziness;
drowsiness, insomnia;
headache;
noise in ears.

Contraindications

bleeding in the brain;
tendency to bleeding (vitamin K deficiency, thrombocytopenia, hemorrhagic diathesis);
bronchial asthma induced by taking salicylates and NSAIDs;
erosive and ulcerative lesions of the gastrointestinal tract (in the acute phase);
gastrointestinal bleeding;
severe renal failure (CK<10 мл/мин);
deficiency of glucose-6-phosphate dehydrogenase;
simultaneous use with methotrexate (>15 mg per week);
1st and 3rd trimesters of pregnancy;
lactation period (breastfeeding);
children and adolescents up to 18 years of age;
hypersensitivity to acetylsalicylic acid, excipients of the drug and other NSAIDs.

Use during pregnancy and breastfeeding

The use of Cardiomagnyl in high doses in the 1st trimester of pregnancy is associated with an increased incidence of fetal developmental defects. In the 2nd trimester of pregnancy, salicylates should only be prescribed based on a strict assessment of risks and benefits. In the 3rd trimester of pregnancy, salicylates in high doses (>300 mg per day) cause inhibition of labor, premature closure of the ductus arteriosus in the fetus, increased bleeding in the mother and fetus, and administration immediately before birth can cause intracranial hemorrhages, especially in premature infants. The administration of salicylates in the 1st and 3rd trimesters of pregnancy is contraindicated.

Salicylates and their metabolites are excreted in small quantities into breast milk. Accidental intake of salicylates during lactation is not accompanied by the development of adverse reactions in the child and does not require cessation of breastfeeding. However, with long-term use of the drug or when it is prescribed in a high dose, breastfeeding should be stopped immediately.

special instructions

You should take the drug Cardiomagnyl after a doctor's prescription.

Acetylsalicylic acid can provoke bronchospasm and also cause attacks bronchial asthma and other hypersensitivity reactions. Risk factors include a history of bronchial asthma, hay fever, nasal polyposis, chronic diseases respiratory system, and allergic reactions(skin rash, itching, urticaria) to other drugs.

Acetylsalicylic acid can cause bleeding of varying severity during and after surgery.

The combination of acetylsalicylic acid with anticoagulants, thrombolytics and antiplatelet drugs is accompanied by an increased risk of bleeding.

Taking acetylsalicylic acid in low doses can provoke the development of gout in predisposed individuals (those with reduced excretion of uric acid).

The combination of acetylsalicylic acid with methotrexate is accompanied by an increased incidence of side effects from the hematopoietic organs.

Taking Cardiomagnyl in high doses has a hypoglycemic effect, which must be kept in mind when prescribing it to patients with diabetes mellitus receiving hypoglycemic agents.

When concomitantly prescribing GCS and salicylates, it should be remembered that during treatment the level of salicylates in the blood is reduced, and after discontinuation of GCS, an overdose of salicylates is possible.

Exceeding the dose of acetylsalicylic acid is associated with the risk of gastrointestinal bleeding.

When acetylsalicylic acid is combined with alcohol, there is an increased risk of damage to the gastrointestinal mucosa and prolongation of bleeding time.

Impact on the ability to drive vehicles and operate machinery

No effect of Cardiomagnyl on the ability of patients to drive vehicles or operate machinery was detected.

Drug interactions

With simultaneous use, acetylsalicylic acid enhances the effect of the following drugs: methotrexate (by reducing renal clearance and displacing it from protein binding), heparin and indirect anticoagulants (by disrupting platelet function and displacing indirect anticoagulants from protein binding), thrombolytic and antiplatelet agents drugs (ticlopidine), digoxin (due to a decrease in its renal excretion), hypoglycemic agents: insulin and sulfonylurea derivatives (due to the hypoglycemic properties of acetylsalicylic acid itself in high doses and displacement of sulfonylurea derivatives from binding with proteins), valproic acid (due to its displacement from connections with proteins).

An additive effect is observed when acetylsalicylic acid is taken simultaneously with ethanol (alcohol).

Acetylsalicylic acid weakens the effect of uricosuric drugs (benzbromarone) due to competitive tubular elimination of uric acid.

By enhancing the elimination of salicylates, systemic corticosteroids weaken their effect.

Antacids and cholestyramine, when used simultaneously, reduce the absorption of the drug Cardiomagnyl.

Analogues of the drug Cardiomagnyl

The drug Cardiomagnyl has no structural analogues for the active substance. However, there is a large number of combination drugs, containing acetylsalicylic acid as an active ingredient, and which can be considered as substitutes for:

Agrenok;
Godasal;
Coplavix.

If there are no analogues of the drug for the active substance, you can follow the links below to the diseases for which the corresponding drug helps, and look at the available analogues for the therapeutic effect.